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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
27.58
Human Site:
Y590
Identified Species:
60.67
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
Y590
F
W
F
G
D
L
N
Y
R
V
D
L
P
T
W
Chimpanzee
Pan troglodytes
XP_526066
929
104074
Y351
Q
K
I
K
Q
Q
Q
Y
A
D
L
L
S
H
D
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
Y610
F
W
F
G
D
L
N
Y
R
L
D
M
D
I
Q
Dog
Lupus familis
XP_542327
1264
138869
Y616
F
W
F
G
D
L
N
Y
R
L
D
M
D
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
Y593
F
W
L
G
D
L
N
Y
R
V
E
L
P
T
W
Rat
Rattus norvegicus
P97573
1190
133575
Y592
F
W
L
G
D
L
N
Y
R
V
E
L
P
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
S441
K
G
G
L
Y
F
L
S
F
H
F
P
F
S
S
Chicken
Gallus gallus
XP_422567
1182
133482
Y589
F
W
L
G
D
L
N
Y
R
V
E
Q
P
P
T
Frog
Xenopus laevis
Q6P4S2
1019
115278
Y441
D
Y
I
E
H
D
I
Y
V
I
G
T
Q
E
D
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
Y594
F
W
F
G
D
L
N
Y
R
L
D
M
D
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
Y592
F
W
L
G
D
L
N
Y
R
I
D
W
N
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
13.3
66.6
66.6
N.A.
86.6
86.6
N.A.
0
66.6
6.6
66.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
13.3
80
80
N.A.
93.3
93.3
N.A.
6.6
73.3
20
80
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
73
10
0
0
0
10
46
0
28
0
19
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
28
0
0
10
0
% E
% Phe:
73
0
37
0
0
10
0
0
10
0
10
0
10
0
0
% F
% Gly:
0
10
10
73
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
19
0
0
0
10
0
0
19
0
0
0
28
0
% I
% Lys:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
37
10
0
73
10
0
0
28
10
37
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% M
% Asn:
0
0
0
0
0
0
73
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
37
10
0
% P
% Gln:
10
0
0
0
10
10
10
0
0
0
0
10
10
0
37
% Q
% Arg:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
28
10
% T
% Val:
0
0
0
0
0
0
0
0
10
37
0
0
0
10
0
% V
% Trp:
0
73
0
0
0
0
0
0
0
0
0
10
0
0
28
% W
% Tyr:
0
10
0
0
10
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _